Outcomes of patients with acute liver failure not listed for liver transplantation: A cohort analysis.

ABSTRACT:

Background

Acute liver failure (ALF) is a rare condition leading to morbidity and mortality. Liver transplantation (LT) is often required, but patients are not always listed for LT. There is a lack of data regarding outcomes in these patients. Our aim is to describe outcomes of patients with ALF not listed for LT and to compare this with those listed for LT.

Methods

Retrospective analysis of all nonlisted patients with ALF enrolled in the Acute Liver Failure Study Group (ALFSG) registry between 1998 and 2018. The primary outcome was 21-day mortality. Multivariable logistic regression was done to identify factors associated with 21-day mortality. The comparison was then made with patients with ALF listed for LT.

Results

A total of 1672 patients with ALF were not listed

SUBMITTER: Dong V 

PROVIDER: S-EPMC11524736 | biostudies-literature | 2024 Nov

REPOSITORIES: biostudies-literature