Neuropsychiatric Symptom Profile in Alzheimer's Disease and Their Relationship With Functional Decline.

ABSTRACT:

Objective

Understanding the course of individual neuropsychiatric symptoms (NPS) and their relationship with function is important for planning targeted interventions for preventing and delaying functional decline. This study aims to disentangle relative contributions of individual NPS on functional decline.

Methods

Longitudinal study of 9,358 well-characterized participants with baseline diagnoses of Mild Cognitive Impairment or AD in the National Alzheimer's Coordinating Center Uniform Data Set. Function was measured using the Functional Assessment Questionnaire (FAQ). Clinician judgment of seven common behavioral symptoms were examined simultaneously: apathy-withdrawal, depressed mood, visual or auditory hallucinations, delusions, disinhibition, irritability, and agitatio

SUBMITTER: Zhu CW 

PROVIDER: S-EPMC11524781 | biostudies-literature | 2024 Dec

REPOSITORIES: biostudies-literature