Smart copper-doped clays in biomimetic microparticles for wound healing and infection control.

ABSTRACT: Chronic wounds are non-healing lesions characterized by a high degree of inflammation, posing significant challenges in clinical management due to the increased risk of severe infection. This study focuses on developing a powder for cutaneous application to enhance the healing and prevent infections in chronic wounds. The smart nanocomposites-based biomimetic microparticles here developed combine the properties of chitosan and of clays and represent a significant innovation in the field of biomaterials for skin regeneration since they possess enhanced antimicrobial properties, are multi-functional scaffolds and promote cell proliferation, support tissue reconstruction by mimicking the natural extracellular matrix, and provide hemostatic properties to control bleeding during wound closure.

SUBMITTER: Ruggeri M 

PROVIDER: S-EPMC11525154 | biostudies-literature | 2024 Dec

REPOSITORIES: biostudies-literature