Maternal-Newborn ABO Blood Groups and Risk of Bacterial Infection in Newborns.

ABSTRACT:

Importance

Newborn immunity largely relies on maternal-fetal transfer of antibodies in utero. Incongruency in ABO blood groups between a mother and newborn may be associated with protection against serious infections, but data specific to newborn bacterial infections are lacking.

Objective

To ascertain the association between maternal-newborn ABO blood group incongruence and lower risk of bacterial infection in newborns.

Design, setting, and participants

This cohort study used linked patient-level datasets for all singleton live births between January 1, 2014, and December 31, 2020, in hospitals and health centers in Ontario, Canada. The cohort comprised maternal-newborn pairs with known ABO blood groups. Data analysis was conducted between February and May 2024.

E

SUBMITTER: Butler EA 

PROVIDER: S-EPMC11525604 | biostudies-literature | 2024 Oct

REPOSITORIES: biostudies-literature