The Modified S-GRAS Scoring System for Prognosis in Korean with Adrenocortical Carcinoma.

ABSTRACT:

Backgruound

Adrenocortical carcinomas (ACCs) are rare tumors with aggressive but varied prognosis. Stage, Grade, Resection status, Age, Symptoms (S-GRAS) score, based on clinical and pathological factors, was found to best stratify the prognosis of European ACC patients. This study assessed the prognostic performance of modified S-GRAS (mS-GRAS) scores including modified grade (mG) by integrating mitotic counts into the Ki67 index (original grade), in Korean ACC patients.

Methods

Patients who underwent surgery for ACC between January 1996 and December 2022 at three medical centers in Korea were retrospectively analyzed. mS-GRAS scores were calculated based on tumor stage, mG (Ki67 index or mitotic counts), resection status, age, and symptoms. Patients were divided into four

SUBMITTER: Baek SK 

PROVIDER: S-EPMC11525693 | biostudies-literature | 2024 Oct

REPOSITORIES: biostudies-literature