Field cycling imaging to characterise breast cancer at low and ultra-low magnetic fields below 0.2 T.

ABSTRACT:

Background

This prospective feasibility study explores Field-Cycling Imaging (FCI), a new MRI technology that measures the longitudinal relaxation time across a range of low magnetic field strengths, providing additional information about the molecular properties of tissues. This study aims to assess the performance of FCI and investigate new quantitative biomarkers at low fields within the context of breast cancer.

Methods

We conducted a study involving 9 people living with breast cancer (10 tumours in total, mean age, 54 ± 10 years). FCI images were obtained at four magnetic field strengths (2.3 mT to 200 mT). FCI images were processed to generate T1 maps and 1/T1 dispersion profiles from regions of tumour, normal adipose tissue, and glandular tissue. The dispersion profil

SUBMITTER: Mallikourti V 

PROVIDER: S-EPMC11526037 | biostudies-literature | 2024 Oct

REPOSITORIES: biostudies-literature