A quasi-experimental analysis comparing antimicrobial usage on COVID-19 and non-COVID-19 wards.

ABSTRACT:

Objective

To describe antimicrobial usage (AMU) trends before and during the coronavirus disease 2019 (COVID-19) pandemic, between COVID-19 and non-COVID-19 wards, and if there was any association with a COVID-19 order set.

Design

Quasi-experimental retrospective interrupted time series analysis of AMU rates with a contemporaneous comparison of COVID-19 versus non-COVID-19 control wards. Analysis using incidence rate ratios (IRR) was conducted using a Poisson regression generalized linear model.

Setting

Five COVID-19 and 4 comparable non-COVID-19 wards and 6 intensive care units (ICUs) at 4 hospitals during pandemic waves 1-4.

Participants

All inpatients receiving systemic antimicrobials.

Intervention

The COVID-19 checkbox antimicrobial order set was imp

SUBMITTER: Doyle D 

PROVIDER: S-EPMC11526180 | biostudies-literature | 2024

REPOSITORIES: biostudies-literature