Association between time to colonoscopy after positive fecal testing and colorectal cancer outcomes in Alberta, Canada.

ABSTRACT:

Objective

To quantify the associations between time to colonoscopy after a positive fecal immunochemical test (FIT+) and colorectal cancer (CRC)-related outcomes in the context of a provincial, population-based CRC screening program.

Setting

Population-based, retrospective cohort study in Alberta, Canada, including Albertans aged 50-74 with at least one FIT+ in 2014-2017.

Methods

Study outcomes were CRC diagnosis after a FIT+ and a diagnostic follow-up colonoscopy in 2014-2019 and CRC stage at diagnosis. Multivariable logistic regression models were used to evaluate the relative risk of any CRC or advanced-stage CRC. Results were presented as crude odds ratio (OR) and adjusted OR (aOR) with 95% confidence intervals (CIs).

Results

Of the 787,967 participants who

SUBMITTER: Brenner DR 

PROVIDER: S-EPMC11526417 | biostudies-literature | 2024 Dec

REPOSITORIES: biostudies-literature