Timely empirical antibiotic therapy against sepsis in a rural Norwegian ambulance service: a prospective cohort study.

ABSTRACT:

Background

Early diagnosis and antibiotic therapy in patients with sepsis reduce morbidity and mortality, thus pre-hospital management is likely to affect patient outcomes. Pre-hospital administration may increase the risk of unnecessary use of broad-spectrum antibiotics, but identification of an infectious focus enables more targeted antibiotic therapy. The aim of this study was to investigate how paramedics, with or without the assistance of general practitioners, can administer empiric intravenous antibiotic treatment against sepsis in a timely manner.

Methods

Cohort study of patients with suspected sepsis that received pre-hospital intravenous antibiotics and were transported to hospital. The setting was mainly rural with long average distance to hospital. Patients recei

SUBMITTER: Andersson LJ 

PROVIDER: S-EPMC11526532 | biostudies-literature | 2024 Oct

REPOSITORIES: biostudies-literature