Neural Correlates of Psychedelic, Sleep, and Sedated States Support Global Theories of Consciousness.

ABSTRACT: Understanding neural mechanisms of consciousness remains a challenging question in neuroscience. A central debate in the field concerns whether consciousness arises from global interactions that involve multiple brain regions or focal neural activity, such as in sensory cortex. Additionally, global theories diverge between the Global Neuronal Workspace (GNW) hypothesis, which emphasizes frontal and parietal areas, and the Integrated Information Theory (IIT), which focuses on information integration within posterior cortical regions. To disentangle the global vs. local and frontoparietal vs. posterior dilemmas, we measured global functional connectivity and local neural synchrony with functional magnetic resonance imaging (fMRI) data across a spectrum of conscious states in humans induced b

SUBMITTER: Dai R 

PROVIDER: S-EPMC11526930 | biostudies-literature | 2024 Oct

REPOSITORIES: biostudies-literature