Competitive interactions shape brain dynamics and computation across species.

ABSTRACT: Adaptive cognition relies on cooperation across anatomically distributed brain circuits. However, specialised neural systems are also in constant competition for limited processing resources. How does the brain's network architecture enable it to balance these cooperative and competitive tendencies? Here we use computational whole-brain modelling to examine the dynamical and computational relevance of cooperative and competitive interactions in the mammalian connectome. Across human, macaque, and mouse we show that the architecture of the models that most faithfully reproduce brain activity, consistently combines modular cooperative interactions with diffuse, long-range competitive interactions. The model with competitive interactions consistently outperforms the cooperative-only model, wi

SUBMITTER: Luppi AI 

PROVIDER: S-EPMC11526968 | biostudies-literature | 2024 Oct

REPOSITORIES: biostudies-literature