Segmented readout for Cherenkov time-of-flight positron emission tomography detectors based on bismuth germanate.

ABSTRACT: Positron emission tomography (PET) is the most sensitive biomedical imaging modality for non-invasively detecting and visualizing positron-emitting radiopharmaceuticals within a subject. In PET, measuring the time-of-flight (TOF) information for each pair of 511-keV annihilation photons improves effective sensitivity but requires high timing resolution. Hybrid materials that emit both scintillation and Cherenkov photons, such as bismuth germanate (BGO), recently offer the potential for more precise timing information from Cherenkov photons while maintaining adequate energy resolution from scintillation photons. However, a significant challenge in using such hybrid materials for TOF PET applications lies in the event-dependent timing spread caused by the mixed detection of Cherenkov and sci

SUBMITTER: Yi M 

PROVIDER: S-EPMC11527102 | biostudies-literature | 2024 Oct

REPOSITORIES: biostudies-literature