Long-Term Exposure to Nitrogen Dioxide and Ozone and Mortality: Update of the WHO Air Quality Guidelines Systematic Review and Meta-Analysis.

ABSTRACT:

Objectives

We performed a systematic review and meta-analysis on long-term exposure to nitrogen dioxide (NO₂) and ozone (O₃) with mortality, to expand evidence that informed 2021 the WHO Air Quality Guidelines and guide the Health Risks of Air Pollution in Europe project.

Methods

We included cohorts investigating NO₂ and O₃ mortality from all-causes, respiratory diseases, chronic obstructive pulmonary disease (COPD), acute lower respiratory infections (ALRI); and NO₂ mortality from circulatory, ischemic heart, cerebrovascular diseases and lung cancer. We pooled estimates by random-effects models and investigated heterogeneity. We assessed the certainty of the evidence using the Grading of Recommendations Assessment Devel

SUBMITTER: Kasdagli MI 

PROVIDER: S-EPMC11527649 | biostudies-literature | 2024

REPOSITORIES: biostudies-literature