Neonatal and early infancy antibiotic exposure is associated with childhood atopic dermatitis, wheeze and asthma.

ABSTRACT: Antibiotics are frequently administered in the neonatal period and early infancy. Little is known about the long-term health consequences of early life antibiotic exposure. The objective is to investigate the association between neonatal and early life (0-6 months) antibiotic treatment and the development of atopic dermatitis, asthma and the use of inhaled corticosteroid medication later in childhood. We analyzed data obtained from hospital records and national registers in a cohort of 11,255 children. The association between early antibiotic exposure and the outcomes were analyzed using logistic regression. Confounding factors were included in the model. Neonatal antibiotic therapy for confirmed infection was associated with childhood atopic dermatitis (adjusted odds ratio 1.49; 95% confi

SUBMITTER: Raty S 

PROVIDER: S-EPMC11527921 | biostudies-literature | 2024 Dec

REPOSITORIES: biostudies-literature