Outcomes of <i>Enterococcus faecalis</i> infective endocarditis according to MIC of amoxicillin: a multicentric study.

ABSTRACT:

Background

The incidence of Enterococcus faecalis infective endocarditis is increasing over time. Data on the impact of minimum inhibitory concentration (MIC) of amoxicillin on treatment outcomes are scarce. The objective of this study was to describe the epidemiology of E. faecalis infective endocarditis and to evaluate whether the MIC of amoxicillin might influence mortality.

Materials

We retrospectively included all consecutive patients diagnosed with definite E. faecalis infective endocarditis between 2013 and 2020 in 11 French hospitals. We extracted data from the local diagnosis-related group (DRG) database and matched these data with microbiological results. Amoxicillin MIC was determined by Etest strip. The primary endpoints were endocarditis-rel

SUBMITTER: Do Rego H 

PROVIDER: S-EPMC11528299 | biostudies-literature | 2024 Dec

REPOSITORIES: biostudies-literature