Objective Pharyngeal Phenotyping in Obstructive Sleep Apnea With High-Resolution Manometry.

ABSTRACT:

Objective

Drug-induced sleep endoscopy (DISE) is a commonly used diagnostic tool for surgical procedural selection in obstructive sleep apnea (OSA), but it is expensive, subjective, and requires sedation. Here we present an initial investigation of high-resolution pharyngeal manometry (HRM) for upper airway phenotyping in OSA, developing a software system that reliably predicts pharyngeal sites of collapse based solely on manometric recordings.

Study design

Prospective cross-sectional study.

Setting

An academic sleep medicine and surgery practice.

Methods

Forty participants underwent simultaneous HRM and DISE. A machine learning algorithm was constructed to estimate pharyngeal level-specific severity of collapse, as determined by an expert DISE reviewer. The pr

SUBMITTER: Kent DT 

PROVIDER: S-EPMC11528336 | biostudies-literature | 2023 Jul

REPOSITORIES: biostudies-literature