Clinical features and treatment of newly diagnosed multiple myeloma with secondary myelofibrosis: a retrospective study.

ABSTRACT:

Background

Secondary myelofibrosis (SMF) is characterized by the excessive deposition of fibrous tissue on top of the primary disease, often causing clinical manifestations to be overshadowed by the primary disease. Unfortunately, current staging systems do not incorporate myelofibrosis, leading to potential treatment delays for SMF.

Objectives

To evaluate the prognosis of patients with multiple myeloma (MM) complicated with myelofibrosis.

Design

The study included the clinical data and treatment results of 208 newly diagnosed multiple myeloma (NDMM) patients who were treated in the Affiliated Hospital of Qingdao University from January 2014 to August 2020, and performed a retrospective analysis.

Methods

All patients underwent bone marrow biopsy, and MF severit

SUBMITTER: Xu H 

PROVIDER: S-EPMC11528636 | biostudies-literature | 2024

REPOSITORIES: biostudies-literature