Associations of HIV and prevalent type 2 diabetes mellitus in the context of obesity in South Africa.

ABSTRACT:

Background

It is unclear how rising obesity among people with HIV (PWH) impacts their risk of type 2 diabetes mellitus (diabetes). We examined associations between HIV, prevalent diabetes and adiposity among South African PWH and their peers without HIV (PWOH).

Methods

HIV status was ascertained by antibody testing. Diabetes was defined as current use of oral hypoglycemics, insulin, and/or HbA1c ≥6.5%. Adiposity was measured by body mass index (BMI), waist circumference and waist-to-height ratio. Their associations were examined using sex-stratified multivariable fractional polynomial generalized linear models, reporting adjusted prevalence and prevalence ratios (adjPR).

Results

The mean age among 1,254 PWH and 4,381 PWOH was 41 years (95%CI 28, 56). The prevalence of

SUBMITTER: Magodoro IM 

PROVIDER: S-EPMC11528680 | biostudies-literature | 2024 Jan-Dec

REPOSITORIES: biostudies-literature