Differences in IgG afucosylation between groups with and without carotid atherosclerosis.

ABSTRACT:

Background

A previous study demonstrated that N-glycosylation profiles of IgG are associated with subclinical atherosclerosis in a British population. However, the generalisability of this finding to other ethnic groups remains to be investigated, and it has yet to account for additional traditional atherosclerotic risk factors. The present study, thus, aims to explore IgG N-glycosylation profiles in Han Chinese with atherosclerosis, and their potential role in atherosclerosis, while controlling for traditional atherosclerotic risk factors.

Methods

Data of this case-control study were obtained from an established umbrella Health Examination Cohort Study (registration number: ChiCTR2100048740). The investigation was conducted at the Health Care Centre of the First Affiliated

SUBMITTER: Tian C 

PROVIDER: S-EPMC11529013 | biostudies-literature | 2024 Nov

REPOSITORIES: biostudies-literature