Evaluation of the sedative properties of oral trazodone, gabapentin or their combination in healthy cats.

ABSTRACT:

Objectives

Sedation before veterinary visits is advocated to help reduce fear and anxiety in cats and facilitate safe handling. The aim of this study was to evaluate the effectiveness of trazodone, gabapentin and a trazodone/gabapentin combination for oral sedation in healthy feline patients before blood donation.

Methods

A total of 21 cats were included in the study. Baseline sedation scores were obtained, and cats were randomly assigned to receive oral trazodone at 5 mg/kg (T), oral gabapentin at 10 mg/kg (G), their combination (TG) or placebo (control group). A sedation score was obtained 1 h after drug administration. A blood sample was obtained at the time of blood collection for quantification of drug plasma concentrations. Agreement between observers was tested with a

SUBMITTER: Tucker LE 

PROVIDER: S-EPMC11529088 | biostudies-literature | 2024 Oct

REPOSITORIES: biostudies-literature