SARS-CoV-2 seroprevalence among people living with HIV in the German HIV-1 Seroconverter Cohort, 2020-2022.

ABSTRACT:

Objectives

People living with HIV (PLWH) are a risk group for severe symptoms and higher mortality during COVID-19. We analyzed the dynamic rise of SARS-CoV-2 seroprevalence induced by coinfections and vaccinations in PLWH in the first three years of the pandemic in Germany and compared it with corresponding data available for the general population.

Methods

Each month on average 93 blood samples from the German HIV-1 Seroconverter Cohort, a prospective longitudinal multicenter study that includes PLWH whose date of seroconversion is well defined, were received. The samples from 1569 PLWH were tested for the presence of anti-S1 and if positive, also for anti-N antibodies.

Results

In 2020 the number of anti-S1 positive cases/month was between 0.0 and 6.9% (average 1.6%

SUBMITTER: Hohn O 

PROVIDER: S-EPMC11529177 | biostudies-literature | 2024 Nov

REPOSITORIES: biostudies-literature