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A modified Delphi exercise in physician-perceived risk factors for drug-induced pneumotoxicity in patients with rheumatological disease.


ABSTRACT:

Background

Drugs used to treat rheumatic disease are associated with pneumotoxicity (drug-induced lung disease), but little is known about associated risk factors.

Aim

To determine expert physician-perceived risk factors for developing pneumotoxicity in patients with rheumatologic conditions.

Methods

A modified international 3-tier Delphi exercise was performed. Tier 1 determined patient and drug variables that physicians perceive to be risk factors. Tier 2 determined degree of risk associated with the Tier-1 derived variables. Tier 3 aimed to internally validate and stratify exemplar cases into risk categories.

Results

134 pulmonologists and 49 rheumatologists responded to Tier 1;157 physicians completed all tiers. Perceived risk factors included: drug type; h

SUBMITTER: Cartlidge MK 

PROVIDER: S-EPMC11529426 | biostudies-literature | 2024 Oct

REPOSITORIES: biostudies-literature

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