High-grade cervical disease and cervical cancer in women aged 50 years and older compared with younger women: examining prevalence by HIV status in two large prospective cohorts in Botswana.

ABSTRACT:

Objectives

International guidelines recommend cervical screening cessation at age 50 following two consecutive negative screens. However, many women aged 50 and older in low-income and middle-income countries (LMICs) have not had prior opportunity to screen. We examine the prevalence of cervical dysplasia and cervical cancer stage in Botswana women aged 50+ compared with 30-49, stratified by HIV status.

Design

Secondary analysis of data from two prospective cohort studies.

Setting

The screening cohort was recruited at health facilities in South East District. The cancer cohort was recruited from the primary public tertiary referral hospital and a private hospital in Gaborone, Botswana.

Participants

The screening cohort included 2570 women aged 30 and older recr

SUBMITTER: Luckett R 

PROVIDER: S-EPMC11529474 | biostudies-literature | 2024 Oct

REPOSITORIES: biostudies-literature