Gas exchange efficiency slopes to assess exercise tolerance in chronic obstructive pulmonary disease.

ABSTRACT:

Background

In patients with chronic obstructive pulmonary disease (COPD), the clinical use of the minute ventilation-carbon dioxide production ([Formula: see text]_E-[Formula: see text]_CO2) slope has been reported as a measure of exercise efficiency, but the oxygen uptake efficiency slope (OUES), i.e., the slope of oxygen uptake ([Formula: see text]_O2) versus the logarithmically transformed [Formula: see text]_E, has rarely been reported.

Methods

We hypothesized that the [Formula: see text]_E-[Formula: see text]_CO2 slope is more useful than OUES in clinical use for the pathophysiological evaluation of COPD. Then, we investigated the cardiopulmonary exercise testing parameters affecting each of these slopes in 122

SUBMITTER: Yanagi H 

PROVIDER: S-EPMC11529499 | biostudies-literature | 2024 Oct

REPOSITORIES: biostudies-literature