Trends in hepatocellular carcinoma and viral hepatitis treatment in older Americans.

ABSTRACT:

Background

Incidence of hepatocellular carcinoma (HCC) had been increasing steadily among older Americans but plateaued in 2015-2017. Chronic infection with hepatitis B virus (HBV) or hepatitis C virus (HCV) are important causes of HCC. The impact of improved treatments for these infections on recent trends in HCC incidence is unclear.

Aims

To examine the relationship between use of antiviral therapy for chronic viral hepatis and HCC incidence in older Americans.

Methods

We used 2007-2017 data from the Surveillance, Epidemiology, and End Results-Medicare database to estimate age-standardized incidence rates and average annual percent changes (AAPCs) for viral hepatitis-attributable HCC among individuals ≥66 years. We analyzed data from Medicare Part D to determine the

SUBMITTER: Jiang J 

PROVIDER: S-EPMC11530004 | biostudies-literature | 2024

REPOSITORIES: biostudies-literature