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Impact of Body Composition on Esophagogastric Junction Opening Measures: Discordant FLIP and Manometric Findings Are More Common With Increased Body Mass Index.


ABSTRACT:

Introduction

Increased intra-abdominal pressure in patients with elevated body mass index (BMI) may affect measurements of esophagogastric junction (EGJ) opening.

Methods

Findings from adult patients who underwent both impedance planimetry with functional luminal imaging probe (FLIP) and high-resolution manometry (HRM) were compared by BMI.

Results

Among patients with no EGJ outflow obstruction on HRM, abnormal EGJ classifications on FLIP were more common among those with elevated than normal BMI (61.1% vs 31.6%, P = 0.037).

Discussion

Discordant results between FLIP and HRM on EGJ opening are more common in patients with elevated BMI. Body composition may impact EGJ function and measures on current testing modalities.

SUBMITTER: Flanagan R 

PROVIDER: S-EPMC11530403 | biostudies-literature | 2024 May

REPOSITORIES: biostudies-literature

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Publications

Impact of Body Composition on Esophagogastric Junction Opening Measures: Discordant FLIP and Manometric Findings Are More Common With Increased Body Mass Index.

Flanagan Ryan R   Muftah Mayssan M   Hiramoto Brent B   Cai Jennifer X JX   Chan Walter W WW  

The American journal of gastroenterology 20240502


<h4>Introduction</h4>Increased intra-abdominal pressure in patients with elevated body mass index (BMI) may affect measurements of esophagogastric junction (EGJ) opening.<h4>Methods</h4>Findings from adult patients who underwent both impedance planimetry with functional luminal imaging probe (FLIP) and high-resolution manometry (HRM) were compared by BMI.<h4>Results</h4>Among patients with no EGJ outflow obstruction on HRM, abnormal EGJ classifications on FLIP were more common among those with e  ...[more]

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