Prognostic nomogram model based on quantitative metrics of subregions surrounding residual cavity in glioblastoma patients.

ABSTRACT:

Background

The hyperintensity area surrounding the residual cavity on postoperative fluid-attenuated inversion recovery (FLAIR) image is a potential site for glioblastoma (GBM) recurrence. This study aimed to develop a nomogram using quantitative metrics from subregions of this area, prior to chemoradiotherapy (CRT), to predict early GBM recurrence.

Methods

Adult patients with GBM diagnosed between October 2018 and October 2022 were retrospectively analyzed. Quantitative metrics, including the mean, maximum, minimum, median values, and standard deviation of FLAIR signal intensity (SI) (measured using 3D-Slicer software), were extracted from the following subregions surrounding the residual cavity on post-contrast T1-weighted (CE-T1WI)-FLAIR fusion images: the enhancing regio

SUBMITTER: Gao L 

PROVIDER: S-EPMC11530551 | biostudies-literature | 2024 Nov

REPOSITORIES: biostudies-literature