Protection effect of cis 9, trans 11-conjugated linoleic acid on oxidative stress and inflammatory damage in bovine mammary epithelial cells.

ABSTRACT: The present study was conducted to observe the protective effects of c9, t11- conjugated linoleic acid (CLA) on oxidative stress and inflammation in bovine mammary epithelial cells (BMECs) exposed to H₂O₂. The BMECs were treated with different concentrations of H₂O₂ for 8 h, 600 µmol/L was determined to be the damage concentration. Using different concentrations of c9, t11-CLA to process BMECs for 24 h, 50 and 100 µmol/L were determined to be the effective concentrations for subsequent analyses. Thus, four BMEC groups were established: Control group; H₂O₂ group; 50 µmol/L c9, t11-CLA + H₂O₂ group; 100 µmol/L c9, t11-CLA + H₂O₂ group. We observed that the H₂O₂

SUBMITTER: Zhang H 

PROVIDER: S-EPMC11530692 | biostudies-literature | 2024 Nov

REPOSITORIES: biostudies-literature