Symptom subtype progression in obstructive sleep apnea over 5 years.

ABSTRACT:

Study objectives

There is limited knowledge regarding the progression or consistency of symptoms in obstructive sleep apnea (OSA) over time. Our objective was to examine the changes in symptom subtypes and identify predictors over a span of 5 years.

Methods

Data of 2,643 participants of the Sleep Heart Health Study with complete baseline and 5-year follow-up visits were analyzed. Latent class analysis on 14 symptoms at baseline and follow-up determined symptom subtypes. Individuals without OSA (apnea-hypopnea index < 5) were incorporated as a known class at each time point. Multinomial logistic regression assessed the effect of age, sex, body mass index, and apnea-hypopnea index on specific class transitions.

Results

The sample consisted of 1,408 females (53.8%) and m

SUBMITTER: Morris JL 

PROVIDER: S-EPMC11530986 | biostudies-literature | 2024 Nov

REPOSITORIES: biostudies-literature