Sex-Specific Association Patterns of Bone Microstructure and Lower Leg Arterial Calcification.

ABSTRACT: In conversations about bone loss and the importance of calcium homeostasis, patients frequently inquire about the association with arterial calcifications. Although a relationship between bone loss and the occurrence of vascular calcifications is suspected, it is not yet fully investigated and understood. This study aims to analyze associations between bone mineralization, structure, and vascular calcification at the lower leg in patients with low bone mineral density in HR-pQCT. We retrospectively analyzed 774 high-resolution quantitative computed tomography (HR-pQCT) scans of the distal tibia for the presence of vascular calcifications. After sex-specific propensity score matching for age and BMI to account for confounders, 132 patients remained for quantification of bone microstructure,

SUBMITTER: Bartosik M 

PROVIDER: S-EPMC11531430 | biostudies-literature | 2024 Nov

REPOSITORIES: biostudies-literature