Network analysis of structural MRI predicts executive function in paediatric traumatic brain injury.

ABSTRACT:

Intro

Paediatric traumatic brain injury (pTBI) is likely to result in cognitive impairment, specifically executive dysfunction. Evidence of the neuroanatomical correlates of this executive function (EF) impairment is derived from studies that treat morphometry of brain regions as distinct, independent features, rather than as a complex network of interrelationships. Morphometric similarity captures the meso-scale organisation of the cortex as the interrelatedness of multiple macro-architectural features and presents a novel tool with which to investigate the brain post pTBI.

Methods

In a retrospective sample (83 pTBI patients, 33 controls), we estimate morphometric similarity from structural MRI by correlating morphometric features between cortical regions. We compared the m

SUBMITTER: Griffiths-King D 

PROVIDER: S-EPMC11531611 | biostudies-literature | 2024 Oct

REPOSITORIES: biostudies-literature