Understanding contrast perception in amblyopia: a psychophysical analysis of the ON and OFF visual pathways.

ABSTRACT:

Purpose

The study aimed to explore potential discrepancies in contrast sensitivity in the ON and OFF visual pathways among individuals with amblyopia compared to controls.

Methods

Eleven adult amblyopes (26.2 ± 4.4 [SD] years old) and 10 controls (24.6 ± 0.8 years old) with normal or corrected to normal visual acuity (logMAR VA ≤ 0) participated in this study. Using the quick contrast sensitivity function (qCSF) algorithm, we measured balanced CSF which would stimulate the ON and OFF pathways unselectively, and CSFs for increments and decrements that would selectively stimulate the ON and OFF visual pathways. Contrast sensitivity and area under log contrast sensitivity function were extracted for statistical analysis.

Results

For the balanced CSF, we found significant

SUBMITTER: Wei J 

PROVIDER: S-EPMC11532024 | biostudies-literature | 2024

REPOSITORIES: biostudies-literature