Transcriptomic and proteomic analysis of resistance to matrine in Oedaleus asiaticus (Orthoptera: Oedipodidae).

ABSTRACT: In order to determine the specific genes and proteins that are affected by matrine and play a role in regulating metabolism in the locust species Oedaleus asiaticus, we conducted RNA-seq, proteomic sequencing, and bioinformatics analyses on third-instar nymphs. These nymphs were divided into two groups: one group was grown under normal conditions, while the other group was treated with matrine. The purpose of this investigation was to gain insight into the molecular mechanisms underlying matrine resistance. Genes and proteins that exhibited differential expression were identified and subjected to analysis using bioinformatics software. The DESeq analysis revealed a total of 743 transcripts that were differentially expressed (DETs). Among these, 208 transcripts were up-regulated, and

SUBMITTER: Han H 

PROVIDER: S-EPMC11532086 | biostudies-literature | 2024 Oct

REPOSITORIES: biostudies-literature