Association between changes in body composition and progression of liver fibrosis in patients with type 2 diabetes mellitus.

ABSTRACT:

Aim

The correlation between type 2 diabetes mellitus (T2DM) and the occurrence of liver fibrosis is well-established. However, the longitudinal association between body composition and liver fibrosis progression in patients with T2DM remains incompletely explored.

Methods

Total of 390 patients with T2DM underwent body composition assessments, followed by a median duration of 2.13 years. The calculated parameters included body mass index (BMI), fat mass index (FMI), trunk fat mass index (TFMI), appendicular skeletal muscle mass index (ASMI), muscle/fat mass ratio (M/F) and appendicular skeletal muscle mass/trunk fat mass ratio (A/T). Liver fibrosis was evaluated through liver stiffness measurement (LSM). Patients were classified according to BMI and body composition, followed

SUBMITTER: Lin Y 

PROVIDER: S-EPMC11532110 | biostudies-literature | 2024

REPOSITORIES: biostudies-literature