Periprocedural hemostatic prophylaxis and outcomes in bleeding disorder of unknown cause.

ABSTRACT:

Background

Bleeding disorder of unknown cause (BDUC) is a diagnostic category encompassing patients with a clear bleeding phenotype but without identifiable abnormality on hemostatic testing. The optimal management of hemostasis in BDUC patients prior to invasive procedures and childbirth is uncertain.

Objectives

Our objective was to characterize periprocedural hemostatic prophylaxis and bleeding outcomes in patients with BDUC.

Methods

We conducted a retrospective cohort study of adult patients with BDUC at 2 academic medical centers. Following diagnosis of BDUC, subsequent surgical procedures and childbirths were analyzed using a combination of registry data and manual chart review.

Results

We identified 127 patients with mean age of 39.9 years (SD = 16.6); th

SUBMITTER: Berkowitz C 

PROVIDER: S-EPMC11532456 | biostudies-literature | 2024 Oct

REPOSITORIES: biostudies-literature