Prognostic value of visceral protein ratios in patients with colon cancer.

ABSTRACT: This study aimed to assess different combinations of visceral proteins and to elucidate their value in predicting progression-free survival (PFS) and overall survival (OS) in patients with colon cancer. The visceral protein ratios included the albumin-globulin ratio (AGR), prealbumin-globulin ratio (PGR), and albumin-prealbumin-globulin ratio (APGR). Compared with AGR and PGR, APGR had the best time-dependent area under the receiver operating characteristic curves for predicting the outcomes. High AGR/PGR/APGR levels were associated with an increased risk of mortality. High AGR (HR = 0.816, 95%CI: 0.719-0.925, p = 0.001), PGR (HR = 0.831, 95%CI: 0.724-0.953, p = 0.008), and APGR (HR = 0.789, 95%CI: 0.688-0.904, p < 0.001) were independent risk factors for PFS. For every SD increase in AGR,

SUBMITTER: Xie H 

PROVIDER: S-EPMC11532831 | biostudies-literature | 2024 Oct

REPOSITORIES: biostudies-literature