Association Between Systolic Blood Pressure Time in Target Range Indices and Adverse Cardiovascular Outcomes.

ABSTRACT:

Background

There is no consensus on optimal time points or systolic blood pressure (SBP) ranges for calculating SBP time in target range (TTR).

Objectives

The purpose of this study was to examine the association between various SBP TTR metrics and long-term major adverse cardiovascular events (MACEs).

Methods

This post hoc analysis of SPRINT (Systolic Blood Pressure Intervention Trial) included participants with complete SBP records and excluded those with events in the initial 2 years. SBP TTR indices were calculated using 3 distinct time points and 3 SBP ranges. The SBP TTR index was the percentage of BP segments within the target SBP ranges. MACE, a composite of heart attack, stroke, heart failure, and cardiovascular death, was the primary outcome.

Results

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SUBMITTER: Li M 

PROVIDER: S-EPMC11533077 | biostudies-literature | 2024 Nov

REPOSITORIES: biostudies-literature