Morphological similarity and white matter structural mapping of new daily persistent headache: a structural connectivity and tract-specific study.

ABSTRACT:

Background

New daily persistent headache (NDPH) is a rare primary headache disorder characterized by daily and persistent sudden onset headaches. Specific abnormalities in gray matter and white matter structure are associated with pain, but have not been well studied in NDPH. The objective of this work is to explore the fiber tracts and structural connectivity, which can help reveal unique gray and white matter structural abnormalities in NDPH.

Methods

The regional radiomics similarity networks were calculated from T1 weighted (T1w) MRI to depict the gray matter structure. The fiber connectivity matrices weighted by diffusion metrics like fractional anisotropy (FA), mean diffusivity (MD) and radial diffusivity (RD) were built, meanwhile the fiber tracts were segmented by ana

SUBMITTER: Zhang D 

PROVIDER: S-EPMC11533401 | biostudies-literature | 2024 Nov

REPOSITORIES: biostudies-literature