Genomic sequencing research in pediatric cancer care: Decision making, attitudes, and perceived utility among adolescents and young adults and their parents.

ABSTRACT:

Purpose

Professional guidelines recommend engaging adolescents and young adults (AYAs) in medical decision making (DM), including whether to undergo genomic sequencing (GS). We explored DM around GS and attitudes after return of GS results among a diverse group of AYAs with cancer and their parents.

Methods

We surveyed AYAs with cancer (n = 75) and their parents (n = 52) 6 months after receiving GS results through the Texas KidsCanSeq study. We analyzed AYAs' DM role in GS research enrollment and their satisfaction with that role. We compared AYAs' and parents' self-reported understanding of, attitudes toward, and perceived utility of the AYA's GS results.

Results

Most AYAs reported equally sharing DM with their parents (55%) or leading DM (36%) about GS research. Com

SUBMITTER: Gutierrez AM 

PROVIDER: S-EPMC11534009 | biostudies-literature | 2024 Aug

REPOSITORIES: biostudies-literature