Modelling the potential impact of global hepatitis B vaccination on the burden of chronic hepatitis B in the United States.

ABSTRACT: About 80% of persons with chronic hepatitis B virus (HBV) infection in the United States are non-US-born. Despite improvements in infant hepatitis B vaccination globally since 2000, work remains to attain the World Health Organization's (WHO) global 2030 goal of 90% vaccination. We explore the impacts on the United States of global progress in hepatitis B vaccination since 2000 and of achieving WHO hepatitis B vaccination goals. We simulated immigrants with HBV infection arriving to the United States from 2000 to 2070 using models of the 10 countries from which the largest numbers of individuals with HBV infection were born. We estimated costs in the United States among these cohorts using a disease simulation model. We simulated three scenarios: a scenario with no progress in infant vacci

SUBMITTER: Hutton DW 

PROVIDER: S-EPMC11534504 | biostudies-literature | 2024 Oct

REPOSITORIES: biostudies-literature