Potential probiotic <i>Lactiplantibacillus plantarum</i> DS1800 extends lifespan and enhances stress resistance in <i>Caenorhabditis elegans</i> model.

ABSTRACT: Probiotics are live microorganisms that provide health benefits when administered in appropriate amounts by improving or restoring the balance of intestinal microbiota. Various functional probiotic products have been developed due to the growing interest in the health-promoting and anti-aging effects of enhancing the gut microbiome. Lactiplantibacillus plantarum species are known for their potential to extend lifespan. However, this activity is strain or isolation source specific, necessitating the identification of individual strain functionalities. This study used the C. elegans model to screen probiotics for life-extension effects and analyze their functions. The 43 lactic-acid bacteria strains isolated from fermented foods, breast milk, and human feces were subjected to l

SUBMITTER: Kim S 

PROVIDER: S-EPMC11534597 | biostudies-literature | 2024

REPOSITORIES: biostudies-literature