Clinical significance of surgical resection for hepatocellular carcinoma with portal vein invasion: a nationwide cohort study.

ABSTRACT:

Background

Hepatocellular carcinoma (HCC) with portal vein invasion (PVI) is considered an advanced stage with a poor prognosis. Although current guidelines recommend systemic treatment for HCC with PVI, surgical resection could produce acceptable outcomes in selected patients. This study aimed to identify the clinical significance of surgical resection for HCC with PVI patients using a large-scale nationwide registry.

Methods

This retrospective, multicenter, observational cohort analyzed data from the Korean Primary Liver Cancer Registry. A total of 16,781 patients who were newly diagnosed with HCC between 2008 and 2018 were enrolled in this study. Patients with worse Child-Turcotte-Pugh scores (≥7) or performance status (≥2) were excluded. Among them, 998 patients who rece

SUBMITTER: Jo HS 

PROVIDER: S-EPMC11534781 | biostudies-literature | 2024 Oct

REPOSITORIES: biostudies-literature