Prophylactic red blood cell transfusions in children and neonates with cancer: An evidence-based clinical practice guideline.

ABSTRACT:

Background

Red blood cell (RBC) transfusions play an important role in supportive care in children and neonates with cancer. However, in current clinical practice, evidence-based recommendations are lacking on when to administer prophylactic RBC transfusions. To address this gap, a clinical practice guideline (CPG) was developed to systematically review the available evidence and provide recommendations for clinicians.

Methods

A systematic literature review in three databases was conducted. The GRADE methodology was used to assess, extract, and summarize the evidence. A multidisciplinary panel of 21 professionals was assembled to ensure comprehensive expertise. If there was insufficient evidence in children with cancer, additional evidence was gathered in general pediatric o

SUBMITTER: Kruimer DM 

PROVIDER: S-EPMC11534970 | biostudies-literature | 2024 Nov

REPOSITORIES: biostudies-literature