Comparison of the urinary microbiome in men who have sex with men with and without Chlamydia trachomatis infection.

ABSTRACT:

Purpose

The urinary tract is colonized by microbial communities that impact urinary health. Previous studies have suggested that the bacterial composition of the male urinary microbiota is related to STIs. This study assessed the bacterial composition of the urinary microbiome in South African MSM with and without C. trachomatis.

Methods

This study used urine samples from MSM attending care at the King Edward VIII hospital and the Aurum Institute in Durban, South Africa. A total of 200 samples were tested for C. trachomatis infection using the Applied Biosystems™ TaqMan^® Assays. Urinary microbiomes of 23 samples were characterized using 16 S rRNA (V3 and V4) gene sequencing on the Illumina MiSeq platform.

Results

Bacterial taxonomic analysis showed a high a

SUBMITTER: Mofolorunsho KC 

PROVIDER: S-EPMC11534976 | biostudies-literature | 2024 Nov

REPOSITORIES: biostudies-literature