Impact of non-invasive ventilation on microbial colonisation patterns in preterm infants: a single-centre study.

ABSTRACT:

Objective

The objective of this study is to assess the relationship between non-invasive ventilation (NIV) and the colonisation of oral and nasal microbiota in preterm infants within the neonatal intensive care unit (NICU).

Design

A prospective cohort study.

Setting

The NICU of Zhejiang University Children's Hospital.

Patients

Patients include preterm infants with a gestational age of 28-35 weeks, enrolled within the first 24 hours of life.

Interventions

Infants were categorised based on respiratory support: NIV, which included nasal continuous positive airway pressure, nasal intermittent positive pressure ventilation or high-flow nasal cannula; and no respiratory support, defined as room air or low-flow nasal cannula at ≤2 L/min.

Main outcome measure

SUBMITTER: Luo F 

PROVIDER: S-EPMC11535706 | biostudies-literature | 2024 Nov

REPOSITORIES: biostudies-literature