Atopic dermatitis and tobacco smoke exposure during childhood and adolescence.

ABSTRACT:

Background

Tobacco smoke may affect atopic dermatitis (AD) because of its known effects on humoral and cellular immunity, but prior studies lack data on disease severity and biomarkers over time.

Objective

We investigated the association between passive and active tobacco smoke exposure (TSE) during childhood and adolescence and the activity and severity of AD.

Methods

A birth cohort of 10,521 individuals was followed through adolescence as part of the Avon Longitudinal Study of Parents and Children. We used mixed-effect models to determine the risk of AD (based on repeated assessments) with passive smoke exposure during childhood, active TSE during adolescence, and using a serum biomarker of tobacco exposure (cotinine) at 3 time points.

Results

After adjusting

SUBMITTER: Al-Alusi NA 

PROVIDER: S-EPMC11536054 | biostudies-literature | 2025 Feb

REPOSITORIES: biostudies-literature