Mortality in patients with major depressive disorder: A nationwide population-based cohort study with 11-year follow-up.

ABSTRACT:

Background

Major depressive disorder (MDD) is a leading cause of disability and premature mortality. This study compared the overall survival (OS) between patients with MDD and non-MDD controls stratified by gender, age, and comorbidities.

Methods

This nationwide population-based cohort study utilized longitudinal patient data (01/01/2010 - 12/31/2020) from the Hungarian National Health Insurance Fund database, which contains healthcare service data for the Hungarian population. Patients with MDD were selected and matched 1:1 to those without MDD using exact matching. The rates of conversion from MDD to bipolar disorder (BD) or schizophrenia were also investigated.

Results

Overall, 471,773 patients were included in each of the matched MDD and non-MDD groups. Patients

SUBMITTER: Bitter I 

PROVIDER: S-EPMC11536202 | biostudies-literature | 2024 Sep

REPOSITORIES: biostudies-literature