Adherence to balanced transfusion among severely injured patients: A post hoc analysis of the RESTRIC trial.

ABSTRACT:

Aim

A balanced transfusion strategy has been a standard resuscitation method for trauma patients, and adherence to a massive transfusion protocol incorporating balanced transfusion is reported to reduce mortality. This study aimed to assess adherence to balanced transfusion among severely injured patients in Japan.

Methods

This study analyzes RESTRIC (restrictive transfusion strategy for critically injured patients) trial patients who were cluster-randomized based on restrictive or liberal transfusion strategy. We defined two transfusion groups: massive transfusion group 1, which includes RBC transfusions of at least eight units within 6 h; and massive transfusion group 2, which includes RBC transfusions of at least 20 units within 24 h. Adherence to balanced transfusion was

SUBMITTER: Aoki M 

PROVIDER: S-EPMC11536327 | biostudies-literature | 2024 Jan-Dec

REPOSITORIES: biostudies-literature