Association between secondhand smoke and liver injury among US non-smoking adults: Mediation analysis of body mass index in the NHANES.

ABSTRACT:

Introduction

Liver injury is a primary factor in the pathogenesis of most liver diseases, which can lead to liver failure. Secondhand smoke (SHS) is a serious public problem. This research explored the correlation between SHS and the indicators of liver injury.

Methods

This cross-sectional study was based on the National Health and Nutrition Examination Survey (NHANES) 2011-2016. The relationship between SHS and indicators of liver injury was explored by the weighted linear regression model and smooth curve fitting. The weighted threshold saturation effect model tested the relationship and inflection point between them. Mediation analyses were used to explore whether body mass index (BMI) mediates the correlation between SHS and liver injury indicators.

Results

Our cr

SUBMITTER: Chen M 

PROVIDER: S-EPMC11536516 | biostudies-literature | 2024

REPOSITORIES: biostudies-literature