Associations between biomarkers and skeletal muscle function in individuals with osteoarthritis: a systematic review and meta-analysis.

ABSTRACT:

Objectives

Skeletal muscle dysfunction is the primary cause of functional limitations in osteoarthritis, associated biomarkers have the potential as targets for early disease identification, diagnosis, and prevention of osteoarthritis disability. This review aimed to identify associations between biomarkers and lower limb skeletal muscle function in individuals with osteoarthritis.

Methods

A systematic literature review and meta-analysis conducted in PubMed, MEDLINE, CINAHL, EMBASE, Scopus, SPORTDiscus and Web of Science databases from inception to 8^th August 2023. Two independent reviewers performed the title, abstract, full-text screening, data extraction and methodological quality assessment. A meta-analysis was undertaken based on the available data.

Result

SUBMITTER: Smith SL 

PROVIDER: S-EPMC11536556 | biostudies-literature | 2024 Nov

REPOSITORIES: biostudies-literature